专利名称：COFORMULATION METHODS AND THEIR
PRODUCTS
发明人：YORK, PETER,WILKINS, SIMON,
ANTHONY,STOREY, RICHARD,ANTHONY,WALKER, STEPHEN,ERNEST,HARLAND, RONALD, SCOTT
申请号：GB0003328申请日：20000831公开号：WO0115664A3公开日：20010920
摘要：A coformulation of an active (preferably pharmaceutically active, for instance aCOX-2 enzyme inhibitor) substance and an oligomeric or polymeric excipient, containingat least 10 % of the active, between 80 and 100 % of which is amorphous. The amorphousphase is stable, with respect to the crystalline phase(s), for at least theree months afterits preparation when stored at between O and 10 DEG C. The invention also providesprocesses, preferably involving SEDS particle formation, for preparing such acoformulation.
申请人：BRADFORD PARTICLE DESIGN PLC,BRISTOL-MYERS SQUIBB COMPANY,YORK,PETER,WILKINS, SIMON, ANTHONY,STOREY, RICHARD, ANTHONY,WALKER, STEPHEN,ERNEST,HARLAND, RONALD, SCOTT
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