专利名称：METHODS AND COMPOSITIONS FOR
PREDICTING THERAPEUTIC EFFICACY OFKINASE INHIBITORS IN PATIENTS WITHMYELODYSPLASTIC SYNDROME ORRELATED DISORDERS
发明人：BENJAMIN TYCKO,AZRA RAZA,FRANCOIS
WILHELM
申请号：US14893935申请日：20140528
公开号：US20160102363A1公开日：20160414
摘要：The invention discloses a diagnostic method for predicting the therapeuticefficacy of a broad specificity kinase inhibitor in a subject with refractory cancercomprising determining the locus-specific DNA methylation profile of the subject,wherein the locus-specific DNA methylation profile predicts the therapeutic efficacy of abroad specificity kinase inhibitor for treatment of a subject with refractory cancer.
申请人：ONCONOVA THERAPEUTICS, INC.,THE TRUSTEES OF COLUMBIA UNIVERSITYIN THE CITY OF NEW YORK
地址：Newtown PA US,New York NY US
国籍：US,US
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